Pathogens… Just the word causes worry amongst
everyone who knows what they are. And in brief, they’re one thing we all want to
keep away from. We not too long ago got the opportunity to speak with Milan Patel, Co-founder and CEO
of PathogenDx, a Scottsdale, AZ primarily based corporation which has created a disruptive
technologies: DNA-primarily based testing for cannabis as properly as other industries.
Verify out the interview under to find out far more
about this technologies and what it implies for cannabis growers and shoppers.
CM: What is
PathogenDx – in a single sentence, and then in depth? What is the technologies in
play right here?
Patel: In a single sentence, PathogenDx is an Arizona biotechnology
corporation that has created a disruptive DNA-primarily based technologies to test for
a number of pathogens (bacterial and fungal organisms that result in contamination) in
a fraction of the time, price and labor to make sure cannabis, hemp, meals, ag, and
water is secure for consumption.
The planet is filled with
dangerous pathogens that increasingly threaten the security of our cannabis, hemp,
meals and water provide. And however, testing labs nevertheless rely on the Petri dishes scientists
invented more than a century ago. At PathogenDx, microbial testing has now been
brought into the modern day age. The company’s patent-winning scientists have
invented a game-altering DNA-primarily based microarray technologies (see image under) that
accelerates the testing identification and quantification of microbes (from
E-coli to powdery mildew)—delivering correct final results in just six hours without the need of
the need to have for enrichment or DNA purification. The corporation entered the Cannabis
marketplace to demonstrate the energy of the Ultra-speedy DNA microarray to prove the
capability of delivering the quickest microbial test in the cannabis sector
whilst meeting the security testing regulations.
CM: The key
tool in testing has constantly been the Petri dish – why adjust that now? How does DNA
come into play?
Patel: The Petri dish has been about for 140 years. Nevertheless, testing final results
take really lengthy due to the fact with a Petri dish, you have to take a sample, enrich
any bacterial or fungal organisms in that sample, streak it on an agar culture
and wait for the cells of the bacterial or fungal pathogens to develop prior to you
get a outcome. This can take anyplace from three days up to 7 days. When you have a
lot of samples coming into a lab, it can be quite unwieldy.
Why adjust now? – The provide chain of
cannabis, hemp, meals, agriculture and water is far more effective now, and with the
solution moving by means of the provide chain a great deal more quickly to the finish buyer, the
threat is larger due to the fact a possible contaminated meals is probably to get consumed
prior to final results are obtained from petri dish testing. This is evident by the
continued increases in meals borne outbreaks in the final two-three decades, and current
examples are the meals borne outbreaks at Chipotle and the Romaine lettuce
incident. Essentially a 19th century resolution can’t meet the demands
and demands of these markets, and a 21st century resolution is required
whereby final results are delivered more quickly prior to contaminated finish solution gets
How does DNA come into play? – DNA comes
into play due to the fact the methodology by which the course of action operates is various in
that it is a targeted method: you do not have to wait for the actual pathogen
cells to develop, you are in a position to recognize that the solution is contaminated at the
molecular level, and you can get a outcome in hours.
Patel: The greatest threats facing farmers and their cannabis/ hemp crops is
continual contamination inside grows with a higher level of presence of each
bacterial and fungal microbes in the finish sample. In addition, we are beginning
to see enhanced presence of viruses – specifically for hemp farmers – which is
wreaking havoc as petri dish testing can’t test for viruses. This final results in
catastrophic losses each from an financial standpoint, as properly as yield
CM: Even even though
PathogenDx was created for hemp and cannabis, you say it can be utilised to
test other agricultural crops, water, even meat and dairy regions. Will the very same
test and process be utilised for various factors what else does PathogenDx need to have
to do to enter the Meals and Dairy sphere?
Patel: We have produced the technologies universally applicable to a number of markets
as properly as ubiquitous, in that at the base level, it is a single course of action. Regardless of whether
you are testing cannabis, romaine, milk, water or something else, the course of action is
proficiently the very same. The content material of the kits are mainly the very same, but
often enhanced with various bacterial or fungal organisms that are
distinct to that sector.
at present submitting the use of the technologies as a certified strategy to the
AOAC for meals and environmental testing at the federal level. We count on to have
certification by mid-2020, and after that occurs, PathogenDx will have access
to a $30B marketplace. In addition, we are building a test that can test up to 20
pathogens that are at present causing high-quality problems in the milk and dairy
sector. We program to introduce a solution in 2020 for this marketplace.
CM: What’s subsequent
for PathogenDx in 2020? Exactly where else do you see application of this technologies?
Patel: We are expanding the applications of the technologies into the Meals,
Environmental, Dairy markets, as properly as introducing a plant pathogen kit that
will broaden the testing capability in cannabis, hemp and Agriculture. The technologies has possible into the a great deal bigger clinical
diagnostics with a multitude of clinical applications. At the present time, the
corporation is functioning with numerous collaborators to evaluate important marketplace